David & Courteney's awkward friendship

The 'Scream' actor admitted it can be uncomfortable seeing coverage of himself and second wife Christina McLarty - with whom he has 21-month-old son Charlie - because it is often accompanied by pictures from his first marriage.

He said: "It's awkward, too -- like, we get married, and there's beautiful pictures of our wedding, and there's also a picture of me and my ex, and it's like, 'Ooh! I've been married before!' "

But the 44-year-old actor is pleased he is still on good terms with Courteney - the mother of his 11-year-old daughter Coco - and will always have "love" for her.

He gushed on 'Kocktails with Khloe': "We have Coquette Productions so we produce things together and work together.

"It's just awesome to work together. I love her. We were married for 13 years or something and we have the baby. You just can't throw all that away."

Elsewhere on the show, David told Khloe Kardashian his sister Alexis Arquette - who was born Robert - declared she no longer wanted to be considered transgender following the host's stepfather's transition from Bruce to Caitlyn last year.

David said: "Alexis is so super wild and after Caitlyn had her transition, she's like 'I'm not transgender anymore'.

"I was like 'What Alexis?' and she said, 'I like to refer to myself as gender suspicious.'

"I said 'You're my sister and brother' and she said 'It depends on how I'm dressed'. 

"I think because of Caitlyn she's like 'I did that already. Now let's take it to the next level'. "